Ueber alkylirte o-Toluidine
نویسندگان
چکیده
منابع مشابه
p-Chloro-o-toluidine and its hydrochloride.
There is limited evidence for the carcinogenicity of p‐chloro-o-toluidine from epidemiological studies in humans. Three cohort studies found high relative risks for urinary-bladder cancer among workers exposed to p-chloro-o-toluidine; however, confounding by coexposure to other potential urinary-bladder carcinogens could not be ruled out. Documented human exposure to p‐chloro-o-toluidine has oc...
متن کاملTetraethylammonium dibromidotricarbonyl(o-toluidine)rhenate(I)
In the title compound, (C(8)H(20)N)[ReBr(2)(C(7)H(9)N)(CO)(3)], the Re(I) atom is octa-hedrally surrounded by three carbonyl ligands orientated in a facial arrangement, two bromide ligands and an o-toluidine ligand. The amine lies trans to the carbonyl ligand and is substitutionally disordered over two positions in a 0.66 (1):0.34 (1) ratio. An array of C-H⋯O, C-H⋯Br and N-H⋯Br hydrogen-bonding...
متن کاملO-Toluidine in Breath-Non-Invasive Prilocaine Monitoring
The generation of methaemoglobin is a rare but potential life-threatening side effect in the use of the local anaesthetic prilocaine. It is currently only possible to ensure the diagnosis by means of blood tests. Rapid noninvasive diagnosis is desirable, especially for risk patients. Using a pig model, we induced methaemoglobinemia via application of dimethyl aminophenol and prilocaine (setup I...
متن کاملBioassay of 4-chloro-o-toluidine hydrochloride for possible carcinogenicity.
A bioassay of 4-chloro-o-toluidine hydrochloride for possible carcinogenicity was conducted by administering the test chemical in feed to F344 rats and B6C3F1 mice. Groups of 50 rats of each sex were administered 4-chloro-o-toluidine in the diet at one of two doses, either 1,250 or 5,000 ppm, for 107 weeks. Groups of 50 mice of each sex were administered the test chemical in the diet at one of ...
متن کاملBioassay of o-toluidine hydrochloride for possible carcinogenicity.
A bioassay of o-toluidine hydrochloride for possible carcinogenicity was conducted by administering the test chemical in feed to F344 rats and B6C3F1 mice. Groups of 50 rats of each sex and 50 mice of each sex were administered o-toluidine hydrochloride at one of several doses, either 3,000 or 6,000 ppm for rats and either 1,000 or 3,000 ppm for the mice, for 101 to 104 weeks. Matched controls ...
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ژورنال
عنوان ژورنال: Justus Liebig's Annalen der Chemie
سال: 1899
ISSN: 0075-4617,1099-0690
DOI: 10.1002/jlac.18993040106